It’s been an amazing decade for technology, but not everyone came out ahead. CrunchGear considers the big losers of the '00s, starting with the biggest: Brick and mortar retailers. Once consumers learned to trust online merchants, lots of stores—we’re looking at you Circuit City and CompUSA—went the way of the dodo, driven out by the lower prices and long-tail advantages of the Internet. So they’re the biggest losers. Runners-up: